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Groupe Retinal degeneration and regeneration : Yvan Arsenijevic
Projets Retinal degeneration and regeneration | Annuaire | Publications | Collaboration

Groupe From physiopathology of retinal diseases to clinical applications : Francine Behar-Cohen
Projets From physiopathology of retinal diseases to clinical applications | Annuaire | Publications | Collaboration

Groupe Retinal nuclear receptors : Pascal Escher
Projets Retinal nuclear receptors | Annuaire | Publications | Collaboration

Groupe Macular degeneration and diabetic retinopathy : Raphael Roduit
Projets Macular degeneration and diabetic retinopathy | Annuaire | Publications | Collaboration

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Groupe "Retinal degeneration and regeneration" -  Publications

Articles 

Arsenijevic Y Cell Cycle Proteins and Retinal Degeneration: Evidences of New Potential Therapeutic Targets 2015 Adv Exp Med Biol. 2016;854:371-7

Kostic C and Arsenijevic Y 2015 Animal modeling for inherited central vision loss. J Pathol. 2015 Sep 21

Yvan Arsenijevic* and Sarah Decembrini An Advocacy for the Use of 3D Stem Cell Culture Systems for the Development of Regenerative Medicine: An Emphasis on Photoreceptor Generation J Stem Cell Res Ther 2015, 5:7

A Askou, L Aagaard, C Kostic, Y Arsenijevic, AK Hollensen, T Bek, TG Jensen, JM and TJ Corydon Multigenic lentiviral vectors for combined and tissue-specific expression of miRNA- and protein-based antiangiogenic factors. Mol Ther 2015 2, 14064; doi:10.1038/mtm.2014.64

Di Gioia SA, Farinelli P, Letteboer SJ, Arsenijevic Y, Sharon D, Roepman R, Rivolta C. Interactome analysis reveals that FAM161A, deficient in recessive retinitis pigmentosa, is a component of the Golgi-centrosomal network. Hum Mol Genet. 2015 Mar 5. pii: ddv085.

Dastpak M, Matin MM, Farshchian M, Arsenijevic Y, Momeni-Moghaddam M, Sisakhtnezhad S, Boozarpour S, Bidkhori HR, Mirahmadi M, Bahrami AR (2014) Construction and Quantitative Evaluation of a Dual Specific Promoter System for Monitoring the Expression Status of Stra8 and c-kit Genes. Mol Biotechnol. 2014 Sep 27. [Epub ahead of print]

S Decembrini, U Koch, A Moulin, F Radtke, Y Arsenijevic (2014) Derivation of traceable and transplantable photoreceptors from embryonic stem cells. Stem cell Reports 22:853-65.

Sarode B, Nowell CS, Jungeun I, Kostic C, Arsenijevic Y, Moulin AP, Schorderet DF, Beermann F, Radtke F. (2014) Notch signaling in the pigmented epithelium of the anterior eye segment promotes ciliary body development at the expense of iris formation. Pigment Cell Melanoma Res. doi: 10.1111/pcmr.12236

C. Kostic, S.G. Lillico, S.V. Crippa,N. Grandchamp,H Pilet,S. Philippe,Z Lu, T. J. King, J. Mallet, C. Sarkis*, Y Arsenijevic*, C.B.A. Whitelaw* (2013) Rapid Cohort Generation and Analysis of Disease Spectrum of Large Animal Model of Cone Dystrophy. PLoS One Aug 19;8(8):e71363
*corresponding authors

M Cachafeiro, A-P Bemelmans, M Samardzija, T Afanasieva, J-A Pournaras, C Grimm, C Kostic, S Philippe, A Wenzel, Y Arsenijevic.(2013) Hyperactivation of retina by light in mice leads to photoreceptors cell death mediated by VEGF and retinal pigment epithelium permeability Cell Death & Dis Aug 29;4:e781

Pipparelli A, Arsenijevic Y, Thuret G, Gain P, Nicolas M, Majo F (2013) ROCK inhibitor enhances adhesion and wound healing of human corneal endothelial cells. PLoS One. Apr23;8(4):e62095.

D Zencak, K Schouwey, D Chen, P Ekström, E Tanger, R Bremner, M van Lohuizen, Arsenijevic Y (2013) Retinal degeneration depends on Bmi1 function and re-activation of cell cycle proteins. Proc. Natl. Acad. Sci USA 110, E593-601.

Askou AL, Pournaras JA, Pihlmann M, Svalgaard JD, Arsenijevic Y, Kostic C, Bek T, Dagnaes-Hansen F, Mikkelsen JG, Jensen TG, Corydon TJ (2012) Reduction of choroidal neovascularization in mice by adeno-associated virus-delivered anti-vascular endothelial growth factor short hairpin RNA. J Gene Med. 11:632-41.

Di Gioia SA, Letteboer SJ, Kostic C, Bandah-Rozenfeld D, Hetterschijt L, Sharon D, Arsenijevic Y, Roepman R, Rivolta C. (2012) FAM161A, associated with retinitis pigmentosa, is a component of the cilia-basal body complex and interacts with proteins involved in ciliopathies. Hum Mol Genet. Dec 1;21(23):5174-84

R Kronstein, J Seebach, S Großklaus, C Minten, B Engelhardt, M Drab, Arsenijevic Y; A Abu Taha, T Afanasieva, Hans Schnittler (2012) Caveolin-1 opens endothelial cell junctions by targeting catenins, Cardiovasc Res 93:130-140.

M. Calame, M. Cachafeiro, S. Philippe, M. Tekaya, D. Wanner, C. Sarkis, C. Kostic, and Y. Arsenijevic (2011) Retinal degeneration progression changes lentiviral vector cell targeting in the retina, PLoS One 2011;6(8):e23782.

Kostic C, Crippa SV, Pignat V, Bemelmans AP, Samardzija M, Grimm C, Wenzel A, Arsenijevic Y.(2011). Gene therapy regenerates protein expression in cone photoreceptors in rpe65 mice.

Buceta M, Galbete JL, Kostic C, Arsenijevic Y, and Mermod N. (2011). Use of human MAR elements to improve retroviral vector production. Gene Therapy, 18, 13-17.

Langmann T, Di Gioia SA, Rau I, Stöhr H, Maksimovic NS, Corbo JC, Renner AB, Zrenner E, Kumaramanickavel G, Karlstetter M, Arsenijevic Y, Weber BH, Gal A, Rivolta C. (2010) Nonsense mutations in FAM161A cause RP28-associated recessive retinitis pigmentosa Amer. J. of Human Genetics, 87, 376-81,

M. Cachafeiro, A.-P. Bemelmans, K. Canola, V. Pignat, S.V. Crippa, C. Kostic, and Y. Arsenijevic (2010). Remaining rod activity mediates visual behaviour in adult Rpe65-/- mice. Invest Ophthalmol Vis Sci .
M Djojosubroto, F Bollotte, P Wirapati, F Radtke, I Stamenkovic, Y Arsenijevic (2009) Chromosomal number aberrations and transformation in adult, but not in neonatal, mouse retinal stem cells in vitro Invest Ophthalmol Vis Sci 50, 5975-87.

A-P Bemelmans, Y Arsenijevic* and F Majo* (2009). Efficient lentiviral gene transfer into corneal stroma cells using a femtosecond laser. Gene Therapy 16, 933-8. *corresponding authors

M Samardzija, N Tanimoto, C Kostic, S Beck, V Oberhauser, S Joly, M Thiersch, E Fahl, Y Arsenijevic, J von Lintig, A Wenzel, M W. Seeliger and C Grimm (2009) Rods Trap 11-cis-Retinal in Conditions of Limited Chromophore Supply Leading to Loss of Cone Function and Cell Death. Hum Mol Gen 18, 1266-75.

Salvi R, Arsenijevic Y, Giacomini M, Rey JP, Voirol MJ, Gaillard RC, Risold PY, Pralong FP (2009) Neurospheres generated from fetal hypothalamus can give rise to cells with a GnRH phenotype. PLoS One 4(2):e4392.

M Bustamante, A Tasinato, F Maurer, I Elkochairi, M Lepore, Y Arsenijevic, T Pedrazzini, F Munier, and Dl Schorderet (2008) Overexpression of a mutant form of TGFBI/BIGH3 induced retinal degeneration in transgenic mice. Mol Vision 14, 1129-37.

Djojosubroto, M & Arsenijevic Y (2008) Retinal stem cell: A promising candidate for retina transplantation. Cell & Tissue Res. 331, 347-57

Pelligrini G, de Luca M, Arsenijevic Y (2007) Towards therapeutic applications of ocular stem cells. Semin Cell Dev Biol 18, 805-18.

Canola K & Arsenijevic Y (2007) Generation of cells committed towards the photoreceptor fate for retinal transplantation. Neuroreport 18: 851-855.

Canola K, Angénieux B, M Tekaya, A Quiambao, MI Naash, Munier FL, Schorderet DF, and Arsenijevic Y (2007) Retinal stem cells transplanted into models of late stages of retinitis pigmentosa preferentially adopt a glial or a retinal ganglion cell fate Invest Ophthalmol Vis Sci 48: 446-454.

A-P Bemelmans, C Kostic, SV Crippa, WW Hauswirth, J Lem, MW Seeliger, A Wenzel and Y Arsenijevic (2006). Lentiviral-mediated transfer of the Rpe65 cDNA rescues both survival and function of cone photoreceptors in a mouse model of Leber Congenital Amaurosis. PLoS Medicine Oct 10;3(10) [Epub ahead of print]

Mehri-Soussi F, Angénieux B, Canola K, Kostic K, and Arsenijevic Y High yield of cells committed to the photoreceptor fate derived from mouse retinal stem cells (2006). Stem Cells 24(9):2060-70 Epub Apr. 27

L El Matri, A Ambresin, Ol Charfi, K Baklouti, F-X Borruat, A Kawasaki, Y Arsenijevic, MW Seeliger, A Wenzel, C Kostic, L Zografos, DF Schorderet, FL Munier (2006). Characterisation of a clumped pigmentary retinal degeneration caused by an R91W homozygous mutation in the RPE65 gene. Graefes Arch Clin Exp Ophthalmol 244:1104-12. Feb 28; [Epub ahead of print]

Angénieux B, Schorderet DF, Arsenijevic Y. (2006) Epidermal growth factor (EGF) is a neuronal differentiation factor for retinal progenitor/stem cells in vitro. Stem Cells 24:696-706. Epub 2005 Sep 22.

DF Schorderet, V Manzi, K Canola, C. Bonny, Y Arsenijevic, FL Munier, F. Maurer. (2005) The D-TAT transporter as an ocular peptide delivery system. Clin Experiment Ophthalmol 33:628-35.

Zencak D, Lingbeek M, Kostic C, Tekaya M, Tanger E, Hornfeld D, Jaquet M, Munier F, Schorderet D, van Lohuizen M, Arsenijevic Y. (2005) Bmi1 loss produces an increase in astroglial cells and a decrease in neural stem/progenitor cell population and proliferation. J. Neurosci . 25:5774-5783.

Vergara MN, Arsenijevic Y, and Del Rio-Tsonis K. (2005) CNS regeneration: a morphogen's tale. J. Neurobiol . 64:491-507

S.W.M. Bruggeman, M.E. Valk-Lingbeek, P.P.M. van der Stoop, J.J.L. Jacobs, K. Kieboom, E. Tanger, D. Hulsman, C.Leung, Y. Arsenijevic, S. Marino and M. van Lohuizen (2005) Ink4a and Arf differentially contribute to Bmi1 deficient phenotypes in the hematopoietic and central nervous system. Genes & Dev. 19, 1438-1443.

Grüter O, Kostic C, Perez M-T, Zografos L, Munier FL, Schorderet DF, Arsenijevic Y (2005) Lentiviral vector-mediated gene transfer in adult mouse photoreceptors is impaired by the presence of a physical barrier. Gene Therapy 12:942-947.

Cui XY, Hu QD, Tekaya M, Shimoda Y, Ang BT, Nie DY, Sun L, Hu WP, Karsak M, Duka T, Takeda Y, Ou LY, Dawe GS, Yu FG, Ahmed S, Jin LH, Schachner M, Watanabe K, Arsenijevic Y, Xiao ZC. (2004) NB-3/Notch1 pathway via Deltex1 promotes neural progenitor cell differentiation into oligodendrocytes. J Biol Chem. 279:25858-65. Epub 2004 Apr 12.

Coles BL, Angenieux B, Inoue T, Del Rio-Tsonis K, Spence JR, McInnes RR, Arsenijevic** Y, van der Kooy** D. (2004) Facile Isolation and the Characterization of Human Retinal Stem Cells. Proc. Natl. Acad. Sci. U.S.A. 101(44):15772-7. Epub 2004 Oct25.
**corresponding authors

Morand S, Buchillier V, Maurer F, Bonny C, Arsenijevic Y, Munier FL, Schorderet DF. (2003) Mutated BIGH3 induces apoptosis in Human Corneal and HeLa cells. Invest Ophthalmol Vis Sci. 44, 2973-2979.

Arsenijevic Y (2003) Mammalian neural stem cell renewal: nature versus nurture. Molecular Neurobioll 27: 73-98.

Arsenijevic Y (2003) Cerveau et régénérescence [Brain and regeneration]. Schw Archiv Neurologie und Psychiatrie 2: 86-90.

Arsenijevic Y, Taverney N, Kostic C, Tekaya M, Zografos L, Schorderet DF, Francis Munier. (2003) Non-neural tissues of the adult human eye: a new source of neurons?Invest Ophthalmol Vis Sci 44: 799-807.

Kostic C, Chiodini F, Salmon P, Wiznerowicz M, , Déglon N, Hornfeld D, Trono D, Aebischer P, Schorderet DF, Munier FL, Arsenijevic Y (2003) Pattern of activity of viral and housekeeping gene promoters using self-inactivating lentivirus vector delivery into the mouse retina. Gene Therapy 10:818-821.

van Adel BA, Kostic C, Déglon N, Ball AK, Arsenijevic Y (2003) Lentiviral-mediated transfer of ciliary neurotrophic factor rescues axotomized retinal ganglion cells. Hum Gene Ther. 14: 103-115.

Marmorstein LY, Munier FL, Arsenijevic Y, Schorderet DF, McLaughlin PJ, Marmorstein AD (2002) Aberrant accumulation of EFEMP1 linked to the retinal pathology in Malattia Leventinese and Aged-Related Macular Degeneration. Proc. Natl. Acad. Sci. U.S.A. 99:13067-13072.

Brunet J-F,, Pellerin L, Arsenijevic Y, Magistretti P, Villemure J-G (2002). A novel method for in vitro production of human glial-like cells from neurosurgical resection tissue. Lab Invest 82:809-812.

Munier FL, Frueh BE, Othenin-Girard P, Uffer S, Cousin P, Wang MX, Heon E, Black GC, Blasi MA, Balestrazzi E, Lorenz B, Escoto R, Barraquer R, Hoeltzenbein M, Gloor B, Fossarello M, Singh AD, Arsenijevic Y, Zografos L, Schorderet DF. (2002). BIGH3 Mutation Spectrum in Corneal Dystrophies. Invest Ophthalmol Vis Sci 43 :949-954.

Arsenijevic Y, Villemure JG, Brunet JF, Bloch JJ, Deglon N, Kostic C, Zurn A, Aebischer P. (2001) Isolation of multipotent neural precursors residing in the cortex of the adult human brain. Exp Neurol. 170: 48-62.

Arsenijevic Y, Weiss S, Schneider B, Aebischer P. (2001) Insulin-like growth factor-I is necessary for neural stem cell proliferation and demonstrates distinct actions of epidermal growth factor and fibroblast growth factor-2. J Neurosci. 21 :7194-7202.

Book chapters and others

Arsenijevic Y (2006) Mammalian neural Stem Cell Renewal. In "Cell Cycle in the Central Nervous System". The Humana Press Inc., Janigro D (ed), pgs 119-139.

D. Zencak, S.V. Crippa, M Tekaya, E. Tanger, D.F. Schorderet, Francis L. Munier, M. van Lohuizen, Y. Arsenijevic (2006) BMI1 loss delays photoreceptor degeneration in RD1 mice, in « Retinal Degenerative Diseases "edited by Joe G. Hollyfield, Robert E. Anderson, and Matthew M. LaVail. Springer, New York, NY, pgs 209-215.

B. Angénieux, L. Michaut, D.F. Schorderet, F.L. Munier, W. Gehring, Y. Arsenijevic (2006) Microarray analysis reveals retinal stem cell characteristics of the adult human eye, in « Retinal Degenerative Diseases "edited by Joe G. Hollyfield, Robert E. Anderson, and Matthew M. LaVail. Springer, New York, NY, pgs 377-380.

A-P Bemelmans, C Kostic, A. Wenzel, M Jaquet, M Seeliger, W. Hauswirth, J Lem, DF Schorderet, FL Munier, Y Arsenijevic (2006) RPE65 promoter activity in the retina of Leber congenital amaurosis genetic mouse models, as revealed by lentiviral-mediated transfer of the GFP gene, in « Retinal Degenerative Diseases "edited by Joe G. Hollyfield, Robert E. Anderson, and Matthew M. LaVail. Springer, New York, NY, pgs 247-253.

Arsenijevic Y (2005) Future Perspectives-Stem Cells: from stem cells and IGF biology to the clinic. In: "The Growth Hormone-Insulin-Like Growth Factor Axis during Development", in Advance in experimental medicine and biology, volume 567. Springer Science+Business Media, Inc., New York, NY", Varela-Nieto I, and Chowen JA (eds). pgs 385-412.

Represa A, and Arsenijevic Y (2000) Les origines des neurones chez l'adulte. La Recherche , 329 : 35-38.




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